Reigning British Open and PGA champion Padraig Harrington bogeyed two of his first four holes and never got on track after the second round of the Buick Invitational at Torrey Pines Golf Course.
Harrington, who is playing in his first tournament of the season after having two non-malignant melanomas removed from near his right eye, carded a 74 to fall 12 shots off the lead held by Camillo Villegas.
Englishman Luke Donald, though, heads a cluster of five players tied for sixth at 139.
Villegas shot a two-under-par 70 to stay atop the leaderboard , the Colombian holding a one-shot lead over the hard-charging John Rollins, whose brilliant eight under 64 was marred by a bogey at the final hole.
A winner of two events last year, including the Tour Championship, Villegas moved to 11-under 133. He shot a blistering nine-under-par 63 in Thursday's first round.
Villegas had extended the lead to six strokes midway through yesterday's round, but Rollins roared into contention with a sensational final nine holes.
Rollins, who started his round on the 10th hole, made up six shots in an eight-hole span on the front side, including a birdie-eagle-birdie spree from numbers four to six.
Bidding for his first title since the 2006 BC Open, Rollins pulled into a tie with Villegas after a birdie at the par-three eighth.
With a chance to grab the outright lead at the par-five ninth, Rollins drove into the rough and hit his third shot into a greenside bunker, forcing him to settle for a bogey and sole possession of second place.
Charley Hoffman also made a late run with birdies on three of the final five holes en route to a six-under 66. He is four shots back and alone in third place at 137.
Paul Goydos (66) and Nick Watney (69) are tied for fourth place at six-under 138. England's Luke Donald (69) heads a cluster of five players at 139.
Aaron Baddeley and Davis Love III, who started the day two shots off the pace, both struggled and fell back in the pack. Baddeley had five bogeys and a double-bogey to fall nine shots off the lead, while Love (77) had six bogeys to drop 10 behind.
Phil Mickelson, who has won this event three times, had a roller-coaster round with four birdies and four bogeys in his even-par 72 to leave him at two-under for the tournament.
Other Europeans include England's Greg Owen who is tied for 50th along with Harrington and Jesper Parnevik of Sweden.
Collated second-round scores (USA unless stated, par 72):
South Course:
137 Charley Hoffman 71 66
138 Paul Goydos 72 66
139 Mathew Goggin (Aus) 69 70, Luke Donald (Eng) 70 69, Bubba Watson 71 68, Jason Gore 70 69
140 Jason Dufner 70 70
141 George McNeill 71 70, Scott Sterling 69 72
142 Phil Mickelson 70 72, Nathan Green (Aus) 70 72, Bill Haas 72 70, Marc Leishman (Aus) 74 68, Ryuji Imada (Jpn) 70 72, Ben Curtis 76 66
143 J.B. Holmes 73 70, Tom Pernice Jnr. 75 68, Charles Howell III 72 71
144 Hunter Mahan 74 70, Dean Wilson 71 73, Fred Couples 74 70
145 Dustin Johnson 74 71, Woody Austin 74 71, Ted Purdy 74 71, Kevin Sutherland 77 68, Greg Owen (Eng) 70 75, Parker McLachlin 74 71, Alex Cejka (Ger) 73 72
146 Pat Perez 73 73, Scott McCarron 74 72, John Senden (Aus) 76 70, Gary Woodland 76 70, Lee Janzen 74 72, David Berganio Jnr. 76 70, Matt Bettencourt 74 72, James Nitties (Aus) 79 67, Y. E Yang (Kor) 77 69, Carl Pettersson (Swe) 77 69, Johnson Wagner 76 70, Tommy Gainey 77 69
-------------------- The following players failed to make the cut ----------------
147 Charlie Wi (Kor) 75 72, Corey Pavin 78 69
148 Patrick Sheehan 74 74, Casey Wittenberg 77 71, Todd Hamilton 74 74, Kevin Streelman 74 74, Leif Olson 75 73, Brandt Jobe 78 70, Carlos Franco (Par) 78 70, Bryce Molder 79 69, Troy Matteson 74 74
149 Steve Marino 78 71, Fredrik Jacobson (Swe) 77 72, Matt Weibring 77 72
150 Scott Gutschewski 78 72, Jimmy Walker 76 74
151 Brendon De Jonge 74 77, Kris Blanks 79 72, Cliff Kresge 78 73
152 Brad Faxon 79 73, Marco Dawson 76 76, Dennis Paulson 78 74, Peter Lonard (Aus) 78 74
153 Jeff Quinney 80 73, Wil Collins 78 75, Rich Beem 78 75, Tom Lehman 75 78, Chez Reavie 76 77, Frank Lickliter II 79 74
154 Rory Sabbatini (Rsa) 76 78, Paul Stankowski 78 76
157 Billy Andrade 82 75, Brendon Todd 81 76
159 Matthew Borchert 82 77
162 Tim Parun 79 83
WD: Arron Oberholser 73
North Course:
133 Camilo Villegas (Col) 63 70
134 John Rollins 70 64
138 Nick Watney 69 69
139 Harrison Frazar 69 70
141 Kent Jones 70 71, J J Henry 70 71, Chris Stroud 73 68
142 Retief Goosen (Rsa) 71 71, Robert Garrigus 68 74, Bart Bryant 73 69, Lucas Glover 69 73, Ricky Barnes 69 73, Aaron Baddeley (Aus) 66 76, D.A. Points 70 72, John Huston 71 71, Stuart Appleby (Aus) 68 74
143 Charles Warren 74 69, Jonathan Kaye 70 73, Davis Love III 66 77, Tag Ridings 71 72, Courtland Lowe 71 72, Matthew Jones (Aus) 70 73, Ben Crane 69 74, Jay Williamson 72 71, Brandt Snedeker 75 68
144 Jeff Klauk 71 73, Aron Price (Aus) 72 72, Tim Petrovic 73 71
145 Gregor Main 70 75, Webb Simpson 72 73, Jarrod Lyle (Aus) 71 74, Rick Price 72 73, Nicholas Thompson 75 70, Jesper Parnevik (Swe) 71 74, Padraig Harrington (Irl) 71 74, Jason Day (Aus) 69 76
146 Brian Bateman 69 77, Rodney Pampling (Aus) 72 74, Jeff Overton 68 78, Colt Knost 73 73, James Driscoll 73 73, Michael Allen 71 75, Arjun Atwal (Ind) 72 74, David Mathis 75 71, Glen Day 72 74
----------------------The following players failed to make the cut --------------
147 Spencer Levin 74 73, Bob Tway 71 76, Peter Tomasulo 73 74, Chris Riley 72 75, Brett Quigley 71 76, Marc Turnesa 71 76, Gregory Casagranda 72 75, Josh Anderson 73 74, Ryan Moore 79 68
148 Aaron Watkins 71 77, Kevin Stadler 71 77, Bill Lunde 74 74, Steve Allan (Aus) 72 76, Briny Baird 70 78
149 Greg Chalmers (Aus) 73 76, John Mallinger 74 75
150 Brad Adamonis 75 75, Kevin Larsen 74 76, Joe Durant 72 78, Brian Vranesh 70 80, John Merrick 74 76, Notah Begay III 75 75, Scott Piercy 75 75
151 Anthony Smith (Aus) 71 80, Darron Stiles 74 77, Troy Kelly 78 73
152 Dudley Hart 73 79, Martin Laird (Sco) 75 77, James Oh (Kor) 74 78
154 Bob Heintz 70 84
155 Tyler Aldridge 74 81
160 Greg Kraft 78 82
WD: Daniel Chopra (Swe) 76, Wes Short Jr 81, Eric Axley 85
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