Stanford, the 2003 ShopRite LPGA Tour Classic winner, had a bogey-free round at Superstition Mountain Golf and Country Club. She had six birdies in a front-nine 30 and birdied the final two holes for a back-nine 32.
The 30-year-old Texan broke the course record of 63 set by Cristie Kerr in 2004, and topped her previous career best of 64 in the first round of the 2006 Canadian Open.
Ochoa, the Mexican star who won the tournament last year for the first of her eight 2007 titles, had nine birdies and two bogeys. She won the HSBC Champions on March 2 in Singapore for her 18th LPGA Tour title.
Sherri Steinhauer was third after a 66, and Karen Stupples, Jee Young Lee and Yani Tseng and Heather Young shot 67s. Annika Sorenstam birdied the final two holes to match Paula Creamer with a 69. Sorenstam shot the first 59 in women's tournament history in her 2001 victory at Moon Valley. The 70-time LPGA Tour winner also won in 2004 and 2005 at Superstition Mountain.
Zurich Classic
AVONDALE, La. (AP) - Refreshed after a couple of weeks off, Dean Wilson birdied three of the last four holes in windy conditions for a 6-under 66 and a one-stroke lead after the first round of the Zurich Classic.
Wilson played eight straight tournaments before taking the break.
Briny Baird, Peter Lonard and Chez Reavie opened with 67s. Baird eagled the par-4 sixth hole, holing out from 208 yards with a 5-wood.
Steve Elkington, Vaughn Taylor, Jay Williamson, Cameron Beckman and John Mallinger opened with 68s, Woody Austin topped a group at 69 and defending champion Nick Watney had a 71 on the TPC Louisiana.
Andalucia Open
PUERTO BANUS, Spain (AP) - Defending champion Lee Westwood shot a 7-under 65 to take a the first-round lead in the European tour's Andalucia Open.
The Englishman had a one-stroke lead over 20-year-old amateur Danny Willett, also from England, and Norway's Jan-Are Larsen on the Aloha Golf Club course. Spanish star Jose Maria Olazabal, playing his first tournament after a nine-month layoff because of rheumatic pain in his shoulders and groin, opened with a 71.